2E2D
Flexibility and variability of TIMP binding: X-ray structure of the complex between collagenase-3/MMP-13 and TIMP-2
Summary for 2E2D
Entry DOI | 10.2210/pdb2e2d/pdb |
Related | 1BQQ 1BR9 1BUV 830C |
Descriptor | Matrix metallopeptidase 13, Metalloproteinase inhibitor 2, ZINC ION, ... (5 entities in total) |
Functional Keywords | matrix metalloproteinase-mmp; collagenase; tissue inhibitor of metalloproteinases-timp; complex, flexibility, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted, extracellular space, extracellular matrix (Probable): P45452 Secreted: P16368 |
Total number of polymer chains | 2 |
Total formula weight | 39011.11 |
Authors | Maskos, K.,Lang, R.,Tschesche, H.,Bode, W. (deposition date: 2006-11-11, release date: 2007-03-13, Last modification date: 2023-08-23) |
Primary citation | Maskos, K.,Lang, R.,Tschesche, H.,Bode, W. Flexibility and Variability of TIMP Binding: X-ray Structure of the Complex Between Collagenase-3/MMP-13 and TIMP-2 J.Mol.Biol., 366:1222-1231, 2007 Cited by PubMed: 17196980DOI: 10.1016/j.jmb.2006.11.072 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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