2E1Q

Crystal Structure of Human Xanthine Oxidoreductase mutant, Glu803Val

Summary for 2E1Q

Entry DOI	10.2210/pdb2e1q/pdb
Descriptor	Xanthine dehydrogenase/oxidase, BICARBONATE ION, CALCIUM ION, ... (9 entities in total)
Functional Keywords	xanthine oxidase, molybdenum cofactor, fad, oxidoreductase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm (By similarity): P47989
Total number of polymer chains	4
Total formula weight	594114.32
Authors	Yamaguchi, Y.,Matsumura, T.,Ichida, K.,Okamoto, K.,Nishino, T. (deposition date: 2006-10-27, release date: 2007-09-18, Last modification date: 2023-10-25)
Primary citation	Yamaguchi, Y.,Matsumura, T.,Ichida, K.,Okamoto, K.,Nishino, T. Human xanthine oxidase changes its substrate specificity to aldehyde oxidase type upon mutation of amino acid residues in the active site: roles of active site residues in binding and activation of purine substrate J.Biochem.(Tokyo), 141:513-524, 2007 Cited by PubMed: 17301077 DOI: 10.1093/jb/mvm053 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation