2DW4
Crystal structure of human LSD1 at 2.3 A resolution
Summary for 2DW4
Entry DOI | 10.2210/pdb2dw4/pdb |
Descriptor | Lysine-specific histone demethylase 1, FLAVIN-ADENINE DINUCLEOTIDE (3 entities in total) |
Functional Keywords | demethylase, amine oxidase, chromatin, histone, androgen, fad, corepressor, oxidoreductase, structural genomics, nppsfa, national project on protein structural and functional analyses, riken structural genomics/proteomics initiative, rsgi |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: O60341 |
Total number of polymer chains | 1 |
Total formula weight | 74235.52 |
Authors | Sengoku, T.,Yokoyama, S.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (deposition date: 2006-08-02, release date: 2007-09-04, Last modification date: 2024-03-13) |
Primary citation | Mimasu, S.,Sengoku, T.,Fukuzawa, S.,Umehara, T.,Yokoyama, S. Crystal structure of histone demethylase LSD1 and tranylcypromine at 2.25A Biochem.Biophys.Res.Commun., 366:15-22, 2008 Cited by PubMed: 18039463DOI: 10.1016/j.bbrc.2007.11.066 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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