2DW4

Crystal structure of human LSD1 at 2.3 A resolution

2DW4 の概要

• エントリーDOI: 10.2210/pdb2dw4/pdb
• 分子名称: Lysine-specific histone demethylase 1, FLAVIN-ADENINE DINUCLEOTIDE (3 entities in total)
• 機能のキーワード: demethylase, amine oxidase, chromatin, histone, androgen, fad, corepressor, oxidoreductase, structural genomics, nppsfa, national project on protein structural and functional analyses, riken structural genomics/proteomics initiative, rsgi
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Nucleus: O60341
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 74235.52

構造登録者

Sengoku, T.,Yokoyama, S.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (登録日: 2006-08-02, 公開日: 2007-09-04, 最終更新日: 2024-03-13)

• 主引用文献: Mimasu, S.,Sengoku, T.,Fukuzawa, S.,Umehara, T.,Yokoyama, S.; Crystal structure of histone demethylase LSD1 and tranylcypromine at 2.25A; Biochem.Biophys.Res.Commun., 366:15-22, 2008; PubMed: 18039463; DOI: 10.1016/j.bbrc.2007.11.066

実験手法

X-RAY DIFFRACTION (2.3 Å)