2DQP

Structural analyses of DNA:DNA and RNA:DNA duplexes containing 5-(N-aminohexyl)carbamoyl modified uridines

2DQP の概要

• エントリーDOI: 10.2210/pdb2dqp/pdb
• 関連するPDBエントリー: 2DQO 2DQQ 479D
• 分子名称: DNA (5'-D(*DCP*(OMU)P*DCP*DTP*(OMU)P*DCP*DTP*DTP*DC)-3'), RNA (5'-R(*GP*AP*AP*GP*AP*AP*GP*AP*G)-3'), (6-AMINOHEXYL)CARBAMIC ACID, ... (4 entities in total)
• 機能のキーワード: modified nucleotide, 5-(n-aminohexyl)carbamoyl-2'-o-methyluridine, a-form rna:dna hybrid duplex, dna-rna hybrid
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 5967.06

構造登録者

Juan, E.C.M.,Kondo, J.,Ito, T.,Ueno, Y.,Matsuda, A.,Takenaka, A. (登録日: 2006-05-29, 公開日: 2007-04-17, 最終更新日: 2023-10-25)

• 主引用文献: Juan, E.C.M.,Kondo, J.,Kurihara, T.,Ito, T.,Ueno, Y.,Matsuda, A.,Takenaka, A.; Crystal structures of DNA:DNA and DNA:RNA duplexes containing 5-(N-aminohexyl)carbamoyl-modified uracils reveal the basis for properties as antigene and antisense molecules; Nucleic Acids Res., 35:1969-1977, 2007; PubMed: 17341465; DOI: 10.1093/nar/gkl821

実験手法

X-RAY DIFFRACTION (2.1 Å)