2DOO

The structure of IMP-1 complexed with the detecting reagent (DansylC4SH) by a fluorescent probe

2DOO の概要

• エントリーDOI: 10.2210/pdb2doo/pdb
• 分子名称: BETA-LACTAMASE IMP-1, ZINC ION, N-[4-({[5-(DIMETHYLAMINO)-1-NAPHTHYL]SULFONYL}AMINO)BUTYL]-3-SULFANYLPROPANAMIDE, ... (4 entities in total)
• 機能のキーワード: metallo-beta-lactamase, protein-inhibitor complex, hydrolase
• 由来する生物種: Serratia marcescens
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 51374.12

構造登録者

Kurosaki, H.,Yamaguchi, Y.,Yasuzawa, H.,Jin, W.,Yamagata, Y.,Arakawa, Y. (登録日: 2006-05-01, 公開日: 2006-11-28, 最終更新日: 2024-03-13)

• 主引用文献: Kurosaki, H.,Yamaguchi, Y.,Yasuzawa, H.,Jin, W.,Yamagata, Y.,Arakawa, Y.; Probing, inhibition, and crystallographic characterization of metallo-beta-lactamase (IMP-1) with fluorescent agents containing dansyl and thiol groups; Chemmedchem, 1:969-972, 2006; PubMed: 16937423; DOI: 10.1002/cmdc.200600115

実験手法

X-RAY DIFFRACTION (2.43 Å)