2DC8

X-ray crystal structure analysis of bovine spleen cathepsin B-CA059 complex

2DC8 の概要

• エントリーDOI: 10.2210/pdb2dc8/pdb
• 関連するPDBエントリー: 1ITO 1QDQ 2DC6 2DC7 2DC9 2DCA 2DCB 2DCC 2DCD
• 分子名称: CATHEPSIN B, PHOSPHATE ION, N-{[(2S,3S)-3-(ETHOXYCARBONYL)OXIRAN-2-YL]CARBONYL}-L-ISOLEUCINE, ... (5 entities in total)
• 機能のキーワード: cathepsin b, cysteine protease, ca059, hydrolase, ec 3.4.22.1
• 由来する生物種: Bos taurus (cattle)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 28379.38

構造登録者

Watanabe, D. (登録日: 2005-12-31, 公開日: 2006-01-24, 最終更新日: 2023-10-25)

• 主引用文献: Watanabe, D.,Yamamoto, A.,Matsumoto, K.,Murata, M.,Kitamura, K.,Tomoo, K.,Ishida, T.; Quantitative estimation of each active subsite of cathepsin B for the inhibitory activity, based on the inhibitory activitybinding mode relationship of a series of epoxysuccinyl inhibitors by X-ray crystal structure analyses of the complexes; To be Published,

実験手法

X-RAY DIFFRACTION (1.94 Å)