2DAA

CRYSTALLOGRAPHIC STRUCTURE OF D-AMINO ACID AMINOTRANSFERASE INACTIVATED BY D-CYCLOSERINE

Summary for 2DAA

• Entry DOI: 10.2210/pdb2daa/pdb
• Descriptor: D-AMINO ACID AMINOTRANSFERASE, D-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-N,O-CYCLOSERYLAMIDE (3 entities in total)
• Functional Keywords: pyridoxal phosphate, pyridoxamine, transaminase, antibiotic, suicide substrate, cycloserine, transferase, aminotransferase
• Biological source: Bacillus sp.
• Total number of polymer chains: 2
• Total formula weight: 65290.28

Authors

Peisach, D.,Chipman, D.M.,Ringe, D. (deposition date: 1997-10-27, release date: 1998-03-18, Last modification date: 2024-05-22)

• Primary citation: Peisach, D.,Chipman, D.M.,Van Ophem, P.W.,Manning, J.M.,Petsko, G.A.,Ringe, D.; D-Cycloserine Inactivation of D-Amino Acid Aminotransferase Leads to a Stable Noncovalent Protein Complex with an Aromatic Cycloserine-Plp Derivative; J.Am.Chem.Soc., 120:2268-2274, 1998

Experimental method

X-RAY DIFFRACTION (2.1 Å)