2D0U

Crystal structure of cyanide bound form of human indoleamine 2,3-dioxygenase

Summary for 2D0U

• Entry DOI: 10.2210/pdb2d0u/pdb
• Related: 2D0T
• Descriptor: Indoleamine 2,3-dioxygenase, CYANIDE ION, PROTOPORPHYRIN IX CONTAINING FE, ... (4 entities in total)
• Functional Keywords: helix bundle, riken structural genomics/proteomics initiative, rsgi, structural genomics, oxidoreductase
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm, cytosol : P14902
• Total number of polymer chains: 2
• Total formula weight: 93447.13

Authors

Sugimoto, H.,Oda, S.,Otsuki, T.,Hino, T.,Yoshida, T.,Shiro, Y.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (deposition date: 2005-08-08, release date: 2006-01-31, Last modification date: 2023-10-25)

• Primary citation: Sugimoto, H.,Oda, S.,Otsuki, T.,Hino, T.,Yoshida, T.,Shiro, Y.; Crystal structure of human indoleamine 2,3-dioxygenase: catalytic mechanism of O2 incorporation by a heme-containing dioxygenase.; Proc.Natl.Acad.Sci.Usa, 103:2611-2616, 2006; PubMed: 16477023; DOI: 10.1073/pnas.0508996103

Experimental method

X-RAY DIFFRACTION (3.4 Å)