2D09
A Role for Active Site Water Molecules and Hydroxyl Groups of Substrate for Oxygen Activation in Cytochrome P450 158A2
Summary for 2D09
Entry DOI | 10.2210/pdb2d09/pdb |
Related | 1S1F 1SE6 1T93 |
Descriptor | putative cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE, FLAVIOLIN, ... (5 entities in total) |
Functional Keywords | streptomyces, cytochrome p450 oxidoreductase, cyp158a2, proton transfer, dioxygen activation, oxidoreductase |
Biological source | Streptomyces coelicolor |
Total number of polymer chains | 1 |
Total formula weight | 45682.52 |
Authors | Zhao, B.,Waterman, M.R. (deposition date: 2005-07-30, release date: 2005-10-25, Last modification date: 2023-10-25) |
Primary citation | Zhao, B.,Guengerich, F.P.,Voehler, M.,Waterman, M.R. Role of active site water molecules and substrate hydroxyl groups in oxygen activation by cytochrome P450 158A2: a new mechanism of proton transfer J.Biol.Chem., 280:42188-42197, 2005 Cited by PubMed: 16239228DOI: 10.1074/jbc.M509220200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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