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2CMW

Structure of Human Casein kinase 1 gamma-1 in complex with 2-(2- Hydroxyethylamino)-6-(3-chloroanilino)-9-isopropylpurine

Summary for 2CMW
Entry DOI10.2210/pdb2cmw/pdb
DescriptorCASEIN KINASE I ISOFORM GAMMA-1, 2-(2-HYDROXYETHYLAMINO)-6-(3-CHLOROANILINO)-9-ISOPROPYLPURINE, PHOSPHATE ION, ... (5 entities in total)
Functional Keywordswnt signaling pathway, serine/threonine-protein kinase, kinase, transferase, atp-binding, phosphorylation, nucleotide-binding, serine/threonine protein kinase
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationCytoplasm: Q9HCP0
Total number of polymer chains1
Total formula weight37337.03
Authors
Bunkoczi, G.,Rellos, P.,Das, S.,Savitsky, P.,Niesen, F.,Sobott, F.,Fedorov, O.,Pike, A.C.W.,von Delft, F.,Sundstrom, M.,Arrowsmith, C.,Edwards, A.,Weigelt, J.,Knapp, S. (deposition date: 2006-05-15, release date: 2006-06-15, Last modification date: 2023-12-13)
Primary citationBunkoczi, G.,Rellos, P.,Das, S.,Savitsky, P.,Niesen, F.,Sobott, F.,Fedorov, O.,Pike, A.C.W.,von Delft, F.,Sundstrom, M.,Arrowsmith, C.,Edwards, A.,Weigelt, J.,Knapp, S.
Structure of Human Casein Kinase 1 Gamma-1 in Complex with 2-(2-Hydroxyethylamino)-6-(3-Chloroanilino)-9-Isopropylpurine (Casp Target)
To be Published,
Experimental method
X-RAY DIFFRACTION (1.75 Å)
Structure validation

226707

數據於2024-10-30公開中

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