2CMR
Crystal structure of the HIV-1 neutralizing antibody D5 Fab bound to the gp41 inner-core mimetic 5-helix
Summary for 2CMR
Entry DOI | 10.2210/pdb2cmr/pdb |
Related | 1AIK 1DF4 1DF5 1DLB 1G9M 1GC1 1GZL 1K33 1K34 1MZI 1OPN 1OPT 1OPW 1RZJ |
Descriptor | TRANSMEMBRANE GLYCOPROTEIN, D5, GLYCEROL, ... (5 entities in total) |
Functional Keywords | immune system, immunoglobulin complex, neutralization, immunoglobulin, envelope protein, hiv, gp41, aids, mhc i, membrane, transmembrane, immunoglobulin domain |
Biological source | HUMAN IMMUNODEFICIENCY VIRUS 1 More |
Total number of polymer chains | 3 |
Total formula weight | 71017.23 |
Authors | Luftig, M.A.,Mattu, M.,Di Giovine, P.,Geleziunas, R.,Hrin, R.,Barbato, G.,Bianchi, E.,Miller, M.D.,Pessi, A.,Carfi, A. (deposition date: 2006-05-11, release date: 2006-10-16, Last modification date: 2023-12-13) |
Primary citation | Luftig, M.A.,Mattu, M.,Di Giovine, P.,Geleziunas, R.,Hrin, R.,Barbato, G.,Bianchi, E.,Miller, M.D.,Pessi, A.,Carfi, A. Structural Basis for HIV-1 Neutralization by a Gp41 Fusion Intermediate-Directed Antibody Nat.Struct.Mol.Biol., 13:740-, 2006 Cited by PubMed: 16862157DOI: 10.1038/NSMB1127 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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