2CMK

CYTIDINE MONOPHOSPHATE KINASE IN COMPLEX WITH CYTIDINE-DI-PHOSPHATE

2CMK の概要

• エントリーDOI: 10.2210/pdb2cmk/pdb
• 関連するPDBエントリー: 1CKE
• 分子名称: PROTEIN (CYTIDINE MONOPHOSPHATE KINASE), SULFATE ION, CYTIDINE-5'-DIPHOSPHATE, ... (4 entities in total)
• 機能のキーワード: nucleotide monophosphate kinase, transferase
• 由来する生物種: Escherichia coli
• 細胞内の位置: Cytoplasm: P0A6I0
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 25373.64

構造登録者

Golinelli-Pimpaneau, B.,Briozzo, P. (登録日: 1998-09-19, 公開日: 1999-09-20, 最終更新日: 2023-12-27)

主引用文献

Briozzo, P.,Golinelli-Pimpaneau, B.,Gilles, A.M.,Gaucher, J.F.,Burlacu-Miron, S.,Sakamoto, H.,Janin, J.,Barzu, O.
Structures of escherichia coli CMP kinase alone and in complex with CDP: a new fold of the nucleoside monophosphate binding domain and insights into cytosine nucleotide specificity.
Structure, 6:1517-1527, 1998

PubMed Abstract: . Nucleoside monophosphate kinases (NMP kinases) catalyze the reversible transfer of a phosphoryl group from a nucleoside triphosphate to a nucleoside monophosphate. Among them, cytidine monophosphate kinase from Escherichia coli has a striking particularity: it is specific for CMP, whereas in eukaryotes a unique UMP/CMP kinase phosphorylates both CMP and UMP with similar efficiency.

PubMed: 9862805
DOI: 10.1016/S0969-2126(98)00150-6

実験手法

X-RAY DIFFRACTION (2 Å)