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2CLS

The crystal structure of the human RND1 GTPase in the active GTP bound state

Summary for 2CLS
Entry DOI10.2210/pdb2cls/pdb
DescriptorRHO-RELATED GTP-BINDING PROTEIN RHO6, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... (4 entities in total)
Functional Keywordsnucleotide-binding, gtp-binding protein rho6, membrane, prenylation, lipoprotein, gtp-binding, cytoskeleton, small gtpase, nucleotide binding protein
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationCell membrane ; Lipid-anchor ; Cytoplasmic side : Q92730
Total number of polymer chains2
Total formula weight45309.74
Authors
Primary citationPike, A.C.W.,Yang, X.,Colebrook, S.,Gileadi, O.,Sobott, F.,Bray, J.,Wen Hwa, L.,Marsden, B.,Zhao, Y.,Schoch, G.,Elkins, J.,Debreczeni, J.E.,Turnbull, A.P.,von Delft, F.,Arrowsmith, C.,Edwards, A.,Weigelt, J.,Sundstrom, M.,Doyle, D.
The Crystal Structure of the Human Rnd1 Gtpase in the Active GTP Bound State
To be Published,
Experimental method
X-RAY DIFFRACTION (2.31 Å)
Structure validation

237735

数据于2025-06-18公开中

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