2CK1

The structure of oxidised cyclophilin A from s. mansoni

2CK1 の概要

• エントリーDOI: 10.2210/pdb2ck1/pdb
• 分子名称: PEPTIDYL-PROLYL CIS-TRANS ISOMERASE E, ACETATE ION (3 entities in total)
• 機能のキーワード: disulphide bridge, cyclophilin, cyclosporin, rotamase activity, rotamase, isomerase, rna-binding, beta-barrel
• 由来する生物種: SCHISTOSOMA MANSONI (BLOOD FLUKE)
• 細胞内の位置: Cytoplasm (By similarity): Q26548
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 19277.14

構造登録者

Gourlay, L.J.,Angelucci, F.,Bellelli, A.,Boumis, G.,Miele, A.E.,Brunori, M. (登録日: 2006-04-10, 公開日: 2007-05-15, 最終更新日: 2023-12-13)

• 主引用文献: Gourlay, L.J.,Angelucci, F.,Baiocco, P.,Boumis, G.,Brunori, M.,Bellelli, A.,Miele, A.E.; The Three-Dimensional Structure of Two Redox States of Cyclophilin-A from Schistosoma Mansoni: Evidence for Redox- Regulation of Peptidyl-Prolyl Cis-Trans Isomerase Activity.; J.Biol.Chem., 282:24851-, 2007; PubMed: 17591771; DOI: 10.1074/JBC.M702714200

実験手法

X-RAY DIFFRACTION (1.8 Å)