2CJF

TYPE II DEHYDROQUINASE INHIBITOR COMPLEX

2CJF の概要

• エントリーDOI: 10.2210/pdb2cjf/pdb
• 関連するPDBエントリー: 1D0I 1GTZ 1GU0 1GU1 1V1J 2BT4
• 分子名称: 3-DEHYDROQUINATE DEHYDRATASE, (1S,4S,5S)-1,4,5-TRIHYDROXY-3-[3-(PHENYLTHIO)PHENYL]CYCLOHEX-2-ENE-1-CARBOXYLIC ACID, GLYCEROL, ... (6 entities in total)
• 機能のキーワード: dehydroquinase, shikimate pathway, dehydroquinate, drug design, lyase, amino-acid biosynthesis, aromatic amino acid biosynthesis
• 由来する生物種: STREPTOMYCES COELICOLOR
• タンパク質・核酸の鎖数: 12
• 化学式量合計: 206684.09

構造登録者

Payne, R.J.,Riboldi-Tunnicliffe, A.,Abell, A.D.,Lapthorn, A.J.,Abell, C. (登録日: 2006-03-31, 公開日: 2007-04-10, 最終更新日: 2023-12-13)

• 主引用文献: Payne, R.J.,Riboldi-Tunnicliffe, A.,Kerbarh, O.,Abell, A.D.,Lapthorn, A.J.,Abell, C.; Design, synthesis, and structural studies on potent biaryl inhibitors of type II dehydroquinases.; Chemmedchem, 2:1010-1013, 2007; PubMed: 17487901; DOI: 10.1002/cmdc.200700062

実験手法

X-RAY DIFFRACTION (1.95 Å)