2CAB

STRUCTURE, REFINEMENT AND FUNCTION OF CARBONIC ANHYDRASE ISOZYMES. REFINEMENT OF HUMAN CARBONIC ANHYDRASE I

「1CAB」から置き換えられました

2CAB の概要

• エントリーDOI: 10.2210/pdb2cab/pdb
• 分子名称: CARBONIC ANHYDRASE FORM B, ZINC ION (2 entities in total)
• 機能のキーワード: hydro-lyase
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasm: P00915
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 28854.42

構造登録者

Kannan, K.K.,Ramanadham, M.,Jones, T.A. (登録日: 1983-10-05, 公開日: 1984-02-02, 最終更新日: 2024-02-14)

主引用文献

Kannan, K.K.,Ramanadham, M.,Jones, T.A.
Structure, refinement, and function of carbonic anhydrase isozymes: refinement of human carbonic anhydrase I
Ann.N.Y.Acad.Sci., 429:49-60, 1984

PubMed Abstract: The structure of human erythrocyte carbonic anhydrase I has been refined to a final R value of 19% to 2-A resolution by a combination of least squares refinement and model fitting in a three-dimensional graphics display. About 300 solvent atoms have been located bound to the protein molecule. An interesting hydrogen bond network involving Zn2+, the liganded solvent, side chain groups of Thr-199, Glu-106, Thr-7, and His-64 through two solvent molecules have been found that may be important for the catalytic mechanism of the carbonic anhydrase.

PubMed: 6430186

実験手法

X-RAY DIFFRACTION (2 Å)