2C8I
Complex Of Echovirus Type 12 With Domains 1, 2, 3 and 4 Of Its Receptor Decay Accelerating Factor (Cd55) By Cryo Electron Microscopy At 16 A
Summary for 2C8I
Entry DOI | 10.2210/pdb2c8i/pdb |
Related | 1H03 1H04 1H2P 1H2Q 1M11 1NWV 1OJV 1OJW 1OJY 1OK1 1OK2 1OK3 1OK9 1UOT 1UPN |
EMDB information | 1182 1183 |
Descriptor | ECHOVIRUS 11 COAT PROTEIN VP1, ECHOVIRUS 11 COAT PROTEIN VP2, ECHOVIRUS 11 COAT PROTEIN VP3, ... (5 entities in total) |
Functional Keywords | picornavirus, daf, virus-receptor complex, antigen, blood group antigen, complement pathway, gpi-anchor, immune response, innate immunity, lipoprotein, plasma, sushi, virus/receptor |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Capsid protein VP0: Virion . Capsid protein VP4: Virion . Capsid protein VP2: Virion . Capsid protein VP3: Virion . Capsid protein VP1: Virion . Protein 2B: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Protein 2C: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Protein 3A: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Protein 3AB: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Viral protein genome-linked: Virion . Protease 3C: Host cytoplasm . Protein 3CD: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . RNA-directed RNA polymerase: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side : P29813 P29813 P29813 P29813 Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Cell membrane; Lipid-anchor, GPI- anchor. Isoform 3: Secreted . Isoform 4: Secreted . Isoform 5: Secreted . Isoform 6: Cell membrane ; Lipid-anchor, GPI-anchor . Isoform 7: Cell membrane ; Lipid-anchor, GPI-anchor : P08174 |
Total number of polymer chains | 5 |
Total formula weight | 127995.66 |
Authors | Pettigrew, D.M.,Williams, D.T.,Kerrigan, D.,Evans, D.J.,Lea, S.M.,Bhella, D. (deposition date: 2005-12-05, release date: 2006-01-17, Last modification date: 2024-05-08) |
Primary citation | Pettigrew, D.M.,Williams, D.T.,Kerrigan, D.,Evans, D.J.,Lea, S.M.,Bhella, D. Structural and Functional Insights Into the Interaction of Echoviruses and Decay-Accelerating Factor. J.Biol.Chem., 281:5169-, 2006 Cited by PubMed: 16272562DOI: 10.1074/JBC.M510362200 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (14 Å) |
Structure validation
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