2C6N
Structure of human somatic angiontensin-I converting enzyme N domain with lisinopril
Summary for 2C6N
Entry DOI | 10.2210/pdb2c6n/pdb |
Related | 2C6F |
Related PRD ID | PRD_000560 |
Descriptor | ANGIOTENSIN-CONVERTING ENZYME, SOMATIC ISOFORM, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total) |
Functional Keywords | hydrolase, angiotensin-i converting enzyme, n domain, zinc metallopeptidase, metalloprotease, angiotensin, lisinopril, carboxypeptidase, glycoprotein, metal-binding, phosphorylation, protease, transmembrane, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 2 |
Total formula weight | 144061.86 |
Authors | Corradi, H.R.,Schwager, S.L.U.,Nichinda, A.,Sturrock, E.D.,Acharya, K.R. (deposition date: 2005-11-10, release date: 2006-03-15, Last modification date: 2023-12-13) |
Primary citation | Corradi, H.R.,Schwager, S.L.,Nchinda, A.T.,Sturrock, E.D.,Acharya, K.R. Crystal structure of the N domain of human somatic angiotensin I-converting enzyme provides a structural basis for domain-specific inhibitor design. J. Mol. Biol., 357:964-974, 2006 Cited by PubMed: 16476442DOI: 10.1016/j.jmb.2006.01.048 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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