2C6H

Crystal structure of YC-17-bound cytochrome P450 PikC (CYP107L1)

2C6H の概要

• エントリーDOI: 10.2210/pdb2c6h/pdb
• 関連するPDBエントリー: 2BVJ 2C7X 2CA0 2CD8
• 分子名称: CYTOCHROME P450 MONOOXYGENASE, PROTOPORPHYRIN IX CONTAINING FE, 4-{[4-(DIMETHYLAMINO)-3-HYDROXY-6-METHYLTETRAHYDRO-2H-PYRAN-2-YL]OXY}-12-ETHYL-3,5,7,11-TETRAMETHYLOXACYCLODODEC-9-ENE-2,8-DIONE, ... (5 entities in total)
• 機能のキーワード: oxidoreductase, cytochrome p450, pikc, cyp107l1, macrolide monooxygenase, antibiotic biosynthesis, heme, iron, metal-binding, monooxygenase, oxidoreductase antibiotic biosynthesis
• 由来する生物種: STREPTOMYCES VENEZUELAE
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 99158.00

構造登録者

Sherman, D.H.,Li, S.,Yermalitskaya, L.V.,Kim, Y.,Smith, J.A.,Waterman, M.R.,Podust, L.M. (登録日: 2005-11-09, 公開日: 2006-07-03, 最終更新日: 2023-12-13)

• 主引用文献: Sherman, D.H.,Li, S.,Yermalitskaya, L.V.,Kim, Y.,Smith, J.A.,Waterman, M.R.,Podust, L.M.; The Structural Basis for Substrate Anchoring, Active Site Selectivity, and Product Formation by P450 Pikc from Streptomyces Venezuelae.; J.Biol.Chem., 281:26289-, 2006; PubMed: 16825192; DOI: 10.1074/JBC.M605478200

実験手法

X-RAY DIFFRACTION (2.35 Å)