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2C5H

X-ray crystal structure of 5'-fluorodeoxyadenosine synthase from Streptomyces cattleya complexed with 2'deoxy-adenosine

Summary for 2C5H
Entry DOI10.2210/pdb2c5h/pdb
Related1RQP 1RQR 2C2W 2C4T 2C4U 2C5B
Descriptor5'-FLUORO-5'-DEOXYADENOSINE SYNTHASE, METHIONINE, (2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-tetrahydro-2-(hydroxymethyl)furan-3-ol, ... (5 entities in total)
Functional Keywordstransferase, fluorinase, 5'-fluorodeoxyadenosine synthase, fla, inhibitor, aza, streptomyces cattleya, sam analogue
Biological sourceSTREPTOMYCES CATTLEYA
Total number of polymer chains3
Total formula weight98292.07
Authors
McEwan, A.R.,Deng, H.,McGlinchey, R.P.,Robinson, D.R.,O'Hagan, D.,Naismith, J.H.,Spencer, J. (deposition date: 2005-10-27, release date: 2006-10-25, Last modification date: 2023-12-13)
Primary citationMcewan, A.R.,Deng, H.,Mcglinchey, R.P.,Robinson, D.R.,O'Hagan, D.,Naismith, J.H.
Substrates and Inhibitors of the Fluorinase from Streptomyces Cattleya
To be Published,
Experimental method
X-RAY DIFFRACTION (2.7 Å)
Structure validation

222036

数据于2024-07-03公开中

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