2C5B

X-ray crystal structure of 5'-fluorodeoxyadenosine synthase from Streptomyces cattleya complexed with 2'deoxy-5'deoxy-fluoroadenosine.

2C5B の概要

• エントリーDOI: 10.2210/pdb2c5b/pdb
• 関連するPDBエントリー: 1RQP 1RQR 2C2W 2C4T 2C4U 2C5H 2CBX 2CC2
• 分子名称: 5'-FLUORO-5'-DEOXYADENOSINE SYNTHASE, METHIONINE, 5'-FLUORO-2',5'-DIDEOXYADENOSINE, ... (4 entities in total)
• 機能のキーワード: transferase, fluorinase, 5'-fluorodeoxyadenosine synthase, fla, inhibitor, aza, streptomyces cattleya, sam analogue
• 由来する生物種: STREPTOMYCES CATTLEYA
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 98411.80

構造登録者

McEwan, A.R.,Deng, H.,McGlinchey, R.P.,Robinson, D.A.,O'Hagan, D.,Naismith, J.H.,Spencer, J. (登録日: 2005-10-26, 公開日: 2007-02-20, 最終更新日: 2023-12-13)

• 主引用文献: Cobb, S.L.,Deng, H.,Mcewan, A.R.,Naismith, J.H.,O'Hagan, D.,Robinson, D.A.; Substrate Specificity in Enzymatic Fluorination. The Fluorinase from Streptomyces Cattleya Accepts 2'-Deoxyadenosine Substrates.; Org.Biomol.Chem., 4:1458-, 2006; PubMed: 16604208; DOI: 10.1039/B600574H

実験手法

X-RAY DIFFRACTION (2.5 Å)