2C3S

Structure Of Sars Cov Main Proteinase At 1.9 A (Ph6.5)

「2BW6」から置き換えられました

2C3S の概要

• エントリーDOI: 10.2210/pdb2c3s/pdb
• 関連するPDBエントリー: 1O5S 1P76 1P9T 1PA5 1PUK 1Q1X 1UJ1 1UK2 1UK3 1UK4 1UW7 1WOF 2AMD 2AMQ 2BX3 2BX4 2D2D
• 分子名称: SARS COV 3C-LIKE PROTEINASE (2 entities in total)
• 機能のキーワード: sars cov, 3c-like protease, main protease, hydrolase
• 由来する生物種: SARS CORONAVIRUS
• 細胞内の位置: Non-structural protein 3: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 4: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 6: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 7: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 8: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 9: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 10: Host cytoplasm, host perinuclear region (By similarity). Helicase: Host endoplasmic reticulum-Golgi intermediate compartment (Potential). Uridylate-specific endoribonuclease: Host cytoplasm, host perinuclear region (By similarity): P59641
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 33876.64

構造登録者

Xu, T.,Ooi, A.,Lee, H.-C.,Lescar, J. (登録日: 2005-10-12, 公開日: 2005-10-18, 最終更新日: 2023-12-13)

• 主引用文献: Xu, T.,Ooi, A.,Lee, H.-C.,Wilmouth, R.,Liu, D.X.,Lescar, J.; Structure of the Sars Coronavirus Main Proteinase as an Active C2 Crystallographic Dimer.; Acta Crystallogr.,Sect.F, 61:964-, 2005; PubMed: 16511208; DOI: 10.1107/S1744309105033257

実験手法

X-RAY DIFFRACTION (1.9 Å)