2C0X

MOLECULAR STRUCTURE OF FD FILAMENTOUS BACTERIOPHAGE REFINED WITH RESPECT TO X-RAY FIBRE DIFFRACTION AND SOLID-STATE NMR DATA

2C0X の概要

• エントリーDOI: 10.2210/pdb2c0x/pdb
• 関連するPDBエントリー: 2C0W
• 分子名称: COAT PROTEIN B (1 entity in total)
• 機能のキーワード: viral protein, filamentous bacteriophage, alpha-helix, membrane proteins, structural protein, transmembrane, helical virus
• 由来する生物種: ENTEROBACTERIA PHAGE FD
• 細胞内の位置: Virion : P69539
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 5212.02

構造登録者

Marvin, D.A.,Welsh, L.C.,Symmons, M.F.,Scott, W.R.P.,Straus, S.K. (登録日: 2005-09-08, 公開日: 2005-12-14, 最終更新日: 2025-01-22)

主引用文献

Marvin, D.A.,Welsh, L.C.,Symmons, M.F.,Scott, W.R.P.,Straus, S.K.
Molecular Structure of Fd (F1, M13) Filamentous Bacteriophage Refined with Respect to X-Ray Fibre Diffraction and Solid-State NMR Data Supports Specific Models of Phage Assembly at the Bacterial Membrane.
J.Mol.Biol., 355:294-, 2006

PubMed Abstract: Filamentous bacteriophage (Inovirus) is a simple and well-characterized model system. The phage particle, or virion, is about 60 angstroms in diameter and several thousand angstrom units long. The virions are assembled at the bacterial membrane as they extrude out of the host without killing it, an example of specific transport of nucleoprotein assemblages across membranes. The Ff group (fd, f1 and M13) has been especially widely studied. Models of virion assembly have been proposed based on a molecular model of the fd virion derived by X-ray fibre diffraction. A somewhat different model of the fd virion using solid-state NMR data has been proposed, not consistent with these models of assembly nor with the X-ray diffraction data. Here we show that reinterpreted NMR data are also consistent with the model derived from X-ray fibre diffraction studies, and discuss models of virion assembly.

PubMed: 16300790
DOI: 10.1016/J.JMB.2005.10.048

実験手法

SOLID-STATE NMR