Solution structure of the TPR domain from Protein phosphatase 5 in complex with Hsp90 derived peptide

Summary for 2BUG

Related1A17 1S95 1WAO
DescriptorSERINE/THREONINE PROTEIN PHOSPHATASE 5, HSP90 (2 entities in total)
Functional Keywordstetratricopeptide domain, protein phosphatase, hsp90 binding, hydrolase, iron, manganese, metal-binding
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationNucleus P53041
Total number of polymer chains2
Total molecular weight16859.09
Cliff, M.J.,Harris, R.,Barford, D.,Ladbury, J.E.,Williams, M.A. (deposition date: 2005-06-13, release date: 2006-03-16, Last modification date: 2011-07-13)
Primary citation
Cliff, M.J.,Harris, R.,Barford, D.,Ladbury, J.E.,Williams, M.A.
Conformational Diversity in the Tpr Domain-Mediated Interaction of Protein Phosphatase 5 with Hsp90.
Structure, 14:415-, 2006
PubMed: 16531226 (PDB entries with the same primary citation)
DOI: 10.1016/J.STR.2005.12.009
MImport into Mendeley
Experimental method
NMR Information

Structure validation

ClashscoreRamachandran outliersSidechain outliers172.5%6.4%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures
Download full validation report