2BU6

crystal structures of human pyruvate dehydrogenase kinase 2 containing physiological and synthetic ligands

2BU6 の概要

• エントリーDOI: 10.2210/pdb2bu6/pdb
• 関連するPDBエントリー: 2BTZ 2BU2 2BU5 2BU7 2BU8
• 分子名称: PYRUVATE DEHYDROGENASE KINASE ISOENZYME 2, (N-{4-[(ETHYLANILINO)SULFONYL]-2-METHYLPHENYL}-3,3,3-TRIFLUORO-2-HYDROXY-2-METHYLPROPANAMIDE (3 entities in total)
• 機能のキーワード: ghkl motif regulation, transferase
• 由来する生物種: HOMO SAPIENS (HUMAN)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 45078.17

構造登録者

Knoechel, T.R.,Tucker, A.D.,Robinson, C.M.,Phillips, C.,Taylor, W.,Bungay, P.J.,Kasten, S.A.,Roche, T.E.,Brown, D.G. (登録日: 2005-06-08, 公開日: 2006-02-02, 最終更新日: 2024-05-08)

• 主引用文献: Knoechel, T.R.,Tucker, A.D.,Robinson, C.M.,Phillips, C.,Taylor, W.,Bungay, P.J.,Kasten, S.A.,Roche, T.E.,Brown, D.G.; Regulatory Roles of the N-Terminal Domain Based on Crystal Structures of Human Pyruvate Dehydrogenase Kinase 2 Containing Physiological and Synthetic Ligands.; Biochemistry, 45:402-, 2006; PubMed: 16401071; DOI: 10.1021/BI051402S

実験手法

X-RAY DIFFRACTION (2.4 Å)