2BK5
Human Monoamine Oxidase B: I199F mutant in complex with isatin
Summary for 2BK5
Entry DOI | 10.2210/pdb2bk5/pdb |
Related | 1GOS 1H8R 1OJ9 1OJA 1OJB 1OJC 1OJD 1S2Q 1S2Y 1S3B 1S3E 2BK3 2BK4 |
Descriptor | AMINE OXIDASE [FLAVIN-CONTAINING] B, FLAVIN-ADENINE DINUCLEOTIDE, ISATIN, ... (4 entities in total) |
Functional Keywords | oxidoreductase, fad-containing amine oxidase, maob acetylation, fad, flavoprotein, maob, transmembrane |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Mitochondrion outer membrane; Single-pass type IV membrane protein; Cytoplasmic side: P27338 |
Total number of polymer chains | 2 |
Total formula weight | 119608.85 |
Authors | Binda, C.,Edmondson, D.E.,Mattevi, A.,Hubalek, F.,Khalil, A.,Li, M.,Castagnoli, N. (deposition date: 2005-02-10, release date: 2005-02-14, Last modification date: 2023-12-13) |
Primary citation | Hubalek, F.,Binda, C.,Khalil, A.,Li, M.,Mattevi, A.,Castagnoli, N.,Edmondson, D.E. Demonstration of Isoleucine 199 as a Structural Determinant for the Selective Inhibition of Human Monoamine Oxidase B by Specific Reversible Inhibitors. J.Biol.Chem., 280:15761-, 2005 Cited by PubMed: 15710600DOI: 10.1074/JBC.M500949200 PDB entries with the same primary citation |
Experimental method |
Structure validation
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