2BHI

Crystal structure of Taiwan cobra cardiotoxin A3 complexed with sulfogalactoceramide

Summary for 2BHI

Entry DOI	10.2210/pdb2bhi/pdb
Related	1H0J 1I02 1XT3 2CRS 2CRT
Descriptor	CYTOTOXIN 3, SULFOGALACTOCERAMIDE, HEXAETHYLENE GLYCOL MONODECYL ETHER, ... (4 entities in total)
Functional Keywords	cardiotoxin, cobra cardiotoxin, sulfogalactoceramide sulfatide, glycosphingolipid, membrane pore formation, cytolysis
Biological source	NAJA ATRA (CHINESE COBRA)
Total number of polymer chains	2
Total formula weight	19073.53
Authors	Wang, C.-H.,Liu, J.-H.,Wu, P.-L.,Lee, S.-C.,Hsiao, C.-D.,Wu, W.-G. (deposition date: 2005-01-12, release date: 2005-11-28, Last modification date: 2023-12-13)
Primary citation	Wang, C.-H.,Liu, J.-H.,Lee, S.-C.,Hsiao, C.-D.,Wu, W.-G. Glycosphingolipid-Facilitated Membrane Insertion and Internalization of Cobra Cardiotoxin: The Sulfatide/Cardiotoxin Complex Structure in a Membrane-Like Environment Suggests a Lipid-Dependent Cell-Penetrating Mechanism for Membrane Binding Polypeptides. J.Biol.Chem., 281:656-, 2006 Cited by PubMed: 16263708 DOI: 10.1074/JBC.M507880200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.31 Å)

Structure validation