2BHI

Crystal structure of Taiwan cobra cardiotoxin A3 complexed with sulfogalactoceramide

2BHI の概要

• エントリーDOI: 10.2210/pdb2bhi/pdb
• 関連するPDBエントリー: 1H0J 1I02 1XT3 2CRS 2CRT
• 分子名称: CYTOTOXIN 3, SULFOGALACTOCERAMIDE, HEXAETHYLENE GLYCOL MONODECYL ETHER, ... (4 entities in total)
• 機能のキーワード: cardiotoxin, cobra cardiotoxin, sulfogalactoceramide sulfatide, glycosphingolipid, membrane pore formation, cytolysis
• 由来する生物種: NAJA ATRA (CHINESE COBRA)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 19073.53

構造登録者

Wang, C.-H.,Liu, J.-H.,Wu, P.-L.,Lee, S.-C.,Hsiao, C.-D.,Wu, W.-G. (登録日: 2005-01-12, 公開日: 2005-11-28, 最終更新日: 2023-12-13)

• 主引用文献: Wang, C.-H.,Liu, J.-H.,Lee, S.-C.,Hsiao, C.-D.,Wu, W.-G.; Glycosphingolipid-Facilitated Membrane Insertion and Internalization of Cobra Cardiotoxin: The Sulfatide/Cardiotoxin Complex Structure in a Membrane-Like Environment Suggests a Lipid-Dependent Cell-Penetrating Mechanism for Membrane Binding Polypeptides.; J.Biol.Chem., 281:656-, 2006; PubMed: 16263708; DOI: 10.1074/JBC.M507880200

実験手法

X-RAY DIFFRACTION (2.31 Å)