2BDM

Structure of Cytochrome P450 2B4 with Bound Bifonazole

2BDM の概要

• エントリーDOI: 10.2210/pdb2bdm/pdb
• 関連するPDBエントリー: 1PO5 1SUO
• 分子名称: Cytochrome P450 2B4, PROTOPORPHYRIN IX CONTAINING FE, 1-[PHENYL-(4-PHENYLPHENYL)-METHYL]IMIDAZOLE, ... (5 entities in total)
• 機能のキーワード: p450, monooxygenase, oxidoreductase, membrane protein, cyp 2b4, cyp lm2
• 由来する生物種: Oryctolagus cuniculus (rabbit)
• 細胞内の位置: Endoplasmic reticulum membrane; Peripheral membrane protein: P00178
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 57695.04

構造登録者

Zhao, Y.,White, M.A.,Muralidhara, B.K.,Sun, L.,Halpert, J.R.,Stout, C.D. (登録日: 2005-10-20, 公開日: 2005-12-27, 最終更新日: 2023-08-23)

• 主引用文献: Zhao, Y.,White, M.A.,Muralidhara, B.K.,Sun, L.,Halpert, J.R.,Stout, C.D.; Structure of microsomal cytochrome P450 2B4 complexed with the antifungal drug bifonazole: insight into P450 conformational plasticity and membrane interaction.; J.Biol.Chem., 281:5973-5981, 2006; PubMed: 16373351; DOI: 10.1074/jbc.M511464200

実験手法

X-RAY DIFFRACTION (2.3 Å)