Loading
PDBj
メニューPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

2B7Z

Structure of HIV-1 protease mutant bound to indinavir

2B7Z の概要
エントリーDOI10.2210/pdb2b7z/pdb
関連するPDBエントリー2B60
分子名称HIV-1 protease, N-[2(R)-HYDROXY-1(S)-INDANYL]-5-[(2(S)-TERTIARY BUTYLAMINOCARBONYL)-4(3-PYRIDYLMETHYL)PIPERAZINO]-4(S)-HYDROXY-2(R)-PHENYLMETHYLPENTANAMIDE (3 entities in total)
機能のキーワードhiv-1, protease, indinavir, drug resistance, active site mutations, non-active site mutations, viral protein
由来する生物種Human immunodeficiency virus 1
細胞内の位置Gag-Pol polyprotein: Host cell membrane ; Lipid-anchor. Matrix protein p17: Virion membrane; Lipid- anchor . Capsid protein p24: Virion . Nucleocapsid protein p7: Virion . Reverse transcriptase/ribonuclease H: Virion . Integrase: Virion : P03367
タンパク質・核酸の鎖数2
化学式量合計22277.20
構造登録者
Clemente, J.C.,Stow, L.R.,Janka, L.K.,Jeung, J.A.,Desai, K.A.,Govindasamy, L.,Agbandje-McKenna, M.,McKenna, R.,Goodenow, M.M.,Dunn, B.M. (登録日: 2005-10-05, 公開日: 2006-11-14, 最終更新日: 2024-02-14)
主引用文献Clemente, J.C.,Stow, L.R.,Janka, L.K.,Jeung, J.A.,Desai, K.A.,Govindasamy, L.,Agbandje-McKenna, M.,McKenna, R.,Goodenow, M.M.,Dunn, B.M.
In vivo, kinetic, and structural analysis of the development of ritonavir resistance
To be Published,
実験手法
X-RAY DIFFRACTION (2.2 Å)
構造検証レポート
Validation report summary of 2b7z
検証レポート(詳細版)ダウンロードをダウンロード

225158

件を2024-09-18に公開中

PDB statisticsPDBj update infoContact PDBjnumon