2B7G

Structure of the Smaug Recognition RNA Element

2B7G の概要

• エントリーDOI: 10.2210/pdb2b7g/pdb
• 関連するPDBエントリー: 2B6G
• 分子名称: 5'-R(*GP*GP*AP*GP*GP*CP*UP*CP*UP*GP*GP*CP*AP*GP*CP*UP*UP*UP*C)-3' (1 entity in total)
• 機能のキーワード: rna, protein-rna complex
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 6086.63

構造登録者

Johnson, P.E.,Donaldson, L.W. (登録日: 2005-10-04, 公開日: 2006-01-24, 最終更新日: 2024-05-22)

主引用文献

Johnson, P.E.,Donaldson, L.W.
RNA recognition by the Vts1p SAM domain
Nat.Struct.Mol.Biol., 13:177-178, 2006

PubMed Abstract: The putative yeast post-transcriptional regulator Vts1p and its related protein Smaug, from Drosophila melanogaster, each use a sterile alpha motif (SAM) domain to bind an RNA hairpin termed the Smaug recognition element (SRE). Here, we present the NMR structures of the Vts1p-SRE complex and the free SRE. Structural highlights include the direct recognition of a guanine base and the formation or stabilization of a base pair in the SRE loop.

PubMed: 16429155
DOI: 10.1038/nsmb1039

実験手法

SOLUTION NMR