2B60

Structure of HIV-1 protease mutant bound to Ritonavir

Summary for 2B60

• Entry DOI: 10.2210/pdb2b60/pdb
• Related: 2B7Z
• Related PRD ID: PRD_001001
• Descriptor: Gag-Pol polyprotein, GLYCEROL, RITONAVIR, ... (4 entities in total)
• Functional Keywords: hiv-1 protease, protease inhibitors, ritonavir, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Human immunodeficiency virus 1
• Total number of polymer chains: 2
• Total formula weight: 22540.58

Authors

Clemente, J.C.,Stow, L.R.,Janka, L.K.,Jeung, J.A.,Desai, K.A.,Govindasamy, L.,Agbandje-McKenna, M.,McKenna, R.,Goodenow, M.M.,Dunn, B.M. (deposition date: 2005-09-29, release date: 2006-11-14, Last modification date: 2024-02-14)

• Primary citation: Clemente, J.C.,Stow, L.R.,Janka, L.K.,Jeung, J.A.,Desai, K.A.,Govindasamy, L.,Agbandje-McKenna, M.,McKenna, R.,Goodenow, M.M.,Dunn, B.M.; In vivo, kinetic, and structural analysis of the development of ritonavir resistance; To be Published,

Experimental method

X-RAY DIFFRACTION (2.2 Å)