2B60
Structure of HIV-1 protease mutant bound to Ritonavir
Summary for 2B60
Entry DOI | 10.2210/pdb2b60/pdb |
Related | 2B7Z |
Related PRD ID | PRD_001001 |
Descriptor | Gag-Pol polyprotein, GLYCEROL, RITONAVIR, ... (4 entities in total) |
Functional Keywords | hiv-1 protease, protease inhibitors, ritonavir, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Human immunodeficiency virus 1 |
Total number of polymer chains | 2 |
Total formula weight | 22540.58 |
Authors | Clemente, J.C.,Stow, L.R.,Janka, L.K.,Jeung, J.A.,Desai, K.A.,Govindasamy, L.,Agbandje-McKenna, M.,McKenna, R.,Goodenow, M.M.,Dunn, B.M. (deposition date: 2005-09-29, release date: 2006-11-14, Last modification date: 2024-02-14) |
Primary citation | Clemente, J.C.,Stow, L.R.,Janka, L.K.,Jeung, J.A.,Desai, K.A.,Govindasamy, L.,Agbandje-McKenna, M.,McKenna, R.,Goodenow, M.M.,Dunn, B.M. In vivo, kinetic, and structural analysis of the development of ritonavir resistance To be Published, |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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