2B0F

NMR Structure of the Human Rhinovirus 3C Protease (serotype 14) with covalently bound Ace-LEALFQ-ethylpropionate inhibitor

2B0F の概要

• エントリーDOI: 10.2210/pdb2b0f/pdb
• 関連するPDBエントリー: 1CQQ 1L1N
• 関連するBIRD辞書のPRD_ID: PRD_000363
• 分子名称: Protease 3C, Ace-LEALFQ-ethylpropionate (2 entities in total)
• 機能のキーワード: beta barrel, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: rhinovirus B14; 詳細
• 細胞内の位置: Protein VP2: Virion. Protein VP3: Virion. Protein VP1: Virion. Protein 2B: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 2C: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3A: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3B: Virion (Potential). Picornain 3C: Host cytoplasm (Potential). RNA-directed RNA polymerase 3D-POL: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential): P03303
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 20823.85

構造登録者

Bjorndahl, T.C.,Andrew, L.C.,Wishart, D.S. (登録日: 2005-09-13, 公開日: 2006-09-05, 最終更新日: 2023-11-15)

• 主引用文献: Bjorndahl, T.C.,Andrew, L.C.,Semenchenko, V.,Wishart, D.S.; NMR solution structures of the apo and peptide-inhibited human rhinovirus 3C protease (Serotype 14): structural and dynamic comparison; Biochemistry, 46:12945-12958, 2007; PubMed: 17944485; DOI: 10.1021/bi7010866

実験手法

SOLUTION NMR