2AYW

Crystal Structure of the complex formed between trypsin and a designed synthetic highly potent inhibitor in the presence of benzamidine at 0.97 A resolution

2AYW の概要

• エントリーDOI: 10.2210/pdb2ayw/pdb
• 分子名称: Cationic trypsin, CALCIUM ION, 2-[2-({[4-(DIAMINOMETHYL)PHENYL]AMINO}CARBONYL)-6-METHOXYPYRIDIN-3-YL]-5-{[(1-FORMYL-2,2-DIMETHYLPROPYL)AMINO]CARBONYL}BENZOIC ACID, ... (7 entities in total)
• 機能のキーワード: trypsin, benzamidine, inhibitor, hydrolase
• 由来する生物種: Bos taurus (cattle)
• 細胞内の位置: Secreted, extracellular space: P00760
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 24839.00

構造登録者

Sherawat, M.,Kaur, P.,Perbandt, M.,Betzel, C.,Slusarchyk, W.A.,Bisacchi, G.S.,Chang, C.,Jacobson, B.L.,Einspahr, H.M.,Singh, T.P. (登録日: 2005-09-09, 公開日: 2006-01-17, 最終更新日: 2023-10-25)

• 主引用文献: Sherawat, M.,Kaur, P.,Perbandt, M.,Betzel, C.,Slusarchyk, W.A.,Bisacchi, G.S.,Chang, C.,Jacobson, B.L.,Einspahr, H.M.,Singh, T.P.; Structure of the complex of trypsin with a highly potent synthetic inhibitor at 0.97 A resolution.; Acta Crystallogr.,Sect.D, 63:500-507, 2007; PubMed: 17372355; DOI: 10.1107/S090744490700697X

実験手法

X-RAY DIFFRACTION (0.97 Å)