2AYL
2.0 Angstrom Crystal Structure of Manganese Protoporphyrin IX-reconstituted Ovine Prostaglandin H2 Synthase-1 Complexed With Flurbiprofen
2AYL の概要
エントリーDOI | 10.2210/pdb2ayl/pdb |
関連するPDBエントリー | 1EQG 1EQH 1HT5 1HT8 1PRH 1Q4G |
分子名称 | Prostaglandin G/H synthase 1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total) |
機能のキーワード | cyclooxygenase, non-steroidal anti-inflammatory drug, peroxidase, prostaglandin synthase, egf-like domain, membrane binding domain, maganese protoporphyrin ix, oxidoreductase |
由来する生物種 | Ovis aries (sheep) |
タンパク質・核酸の鎖数 | 2 |
化学式量合計 | 135842.83 |
構造登録者 | |
主引用文献 | Gupta, K.,Selinsky, B.S.,Loll, P.J. 2.0 angstroms structure of prostaglandin H2 synthase-1 reconstituted with a manganese porphyrin cofactor. Acta Crystallogr.,Sect.D, 62:151-156, 2006 Cited by PubMed: 16421446DOI: 10.1107/S0907444905036309 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (2 Å) |
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