2AU7

The R43Q active site variant of E.coli inorganic pyrophosphatase

Summary for 2AU7

• Entry DOI: 10.2210/pdb2au7/pdb
• Related: 2AU6 2AU8 2AU9
• Descriptor: Inorganic pyrophosphatase, PHOSPHATE ION, MANGANESE (II) ION, ... (6 entities in total)
• Functional Keywords: hydrolase, mutant, inorganic pyrophosphatase
• Biological source: Escherichia coli
• Cellular location: Cytoplasm: P0A7A9
• Total number of polymer chains: 1
• Total formula weight: 20090.68

Authors

Samygina, V.R.,Avaeva, S.M.,Bartunik, H.D. (deposition date: 2005-08-27, release date: 2006-08-29, Last modification date: 2021-11-10)

• Primary citation: Samygina, V.R.,Moiseev, V.M.,Rodina, E.V.,Vorobyeva, N.N.,Popov, A.N.,Kurilova, S.A.,Nazarova, T.I.,Avaeva, S.M.,Bartunik, H.D.; Reversible inhibition of Escherichia coli inorganic pyrophosphatase by fluoride: trapped catalytic intermediates in cryo-crystallographic studies; J.Mol.Biol., 366:1305-1317, 2007; PubMed: 17196979; DOI: 10.1016/j.jmb.2006.11.082

Experimental method

X-RAY DIFFRACTION (1.05 Å)