2AQJ

The structure of tryptophan 7-halogenase (PrnA) suggests a mechanism for regioselective chlorination

Summary for 2AQJ

• Entry DOI: 10.2210/pdb2aqj/pdb
• Related: 2APG
• Descriptor: tryptophan halogenase, PrnA, CHLORIDE ION, TRYPTOPHAN, ... (5 entities in total)
• Functional Keywords: tryptophan 7-halogenase, flavin-dependent halogenase, helical bundle, sandwiched sheets, structural genomics, scottish structural proteomics facility, sspf, biosynthetic protein
• Biological source: Pseudomonas fluorescens
• Total number of polymer chains: 1
• Total formula weight: 62171.31

Authors

Dong, C.,Flecks, S.,Unversucht, S.,Haupt, C.,Van Pee, K.-H.,Naismith, J.H.,Scottish Structural Proteomics Facility (SSPF) (deposition date: 2005-08-18, release date: 2005-10-04, Last modification date: 2024-02-14)

• Primary citation: Dong, C.,Flecks, S.,Unversucht, S.,Haupt, C.,van Pee, K.H.,Naismith, J.H.; Tryptophan 7-halogenase (PrnA) structure suggests a mechanism for regioselective chlorination.; Science, 309:2216-2219, 2005; PubMed: 16195462; DOI: 10.1126/science.1116510

Experimental method

X-RAY DIFFRACTION (1.8 Å)