2AQ1

Crystal structure of T-cell receptor V beta domain variant complexed with superantigen SEC3 mutant

Summary for 2AQ1

• Entry DOI: 10.2210/pdb2aq1/pdb
• Related: 1JCK 2APB 2APF 2APT 2APV 2APW 2APX 2AQ2 2AQ3
• Descriptor: T-cell receptor beta chain V, Enterotoxin type C-3 (3 entities in total)
• Functional Keywords: t-cell receptor, staphylococcal enterotoxin c3, superantigen, complex (toxin-receptor), immune system
• Biological source: Mus musculus (house mouse); More
• Cellular location: Secreted: P0A0L5
• Total number of polymer chains: 8
• Total formula weight: 159458.00

Authors

Cho, S.,Swaminathan, C.P.,Yang, J.,Kerzic, M.C.,Guan, R.,Kieke, M.C.,Kranz, D.M.,Mariuzza, R.A.,Sundberg, E.J. (deposition date: 2005-08-17, release date: 2006-03-21, Last modification date: 2017-10-11)

• Primary citation: Cho, S.,Swaminathan, C.P.,Yang, J.,Kerzic, M.C.,Guan, R.,Kieke, M.C.,Kranz, D.M.,Mariuzza, R.A.,Sundberg, E.J.; Structural basis of affinity maturation and intramolecular cooperativity in a protein-protein interaction.; Structure, 13:1775-1787, 2005; PubMed: 16338399; DOI: 10.1016/j.str.2005.08.015

Experimental method

X-RAY DIFFRACTION (2.1 Å)