2APT

Crystal Structure of the G17E/S54N/K66E/Q72H/E80V/L81S/T87S/G96V variant of the murine T cell receptor V beta 8.2 domain

Summary for 2APT

• Entry DOI: 10.2210/pdb2apt/pdb
• Related: 2APB 2APF 2APV 2APW 2APX 2AQ1 2AQ2 2AQ3
• Descriptor: T-cell receptor beta chain V, MALONIC ACID (3 entities in total)
• Functional Keywords: the murine t cell receptor v beta 8.2 domain, immune system
• Biological source: Rattus norvegicus (Norway rat)
• Total number of polymer chains: 2
• Total formula weight: 24416.92

Authors

Cho, S.,Swaminathan, C.P.,Yang, J.,Kerzic, M.C.,Guan, R.,Kieke, M.C.,Kranz, D.M.,Mariuzza, R.A.,Sundberg, E.J. (deposition date: 2005-08-16, release date: 2006-03-21, Last modification date: 2018-04-04)

• Primary citation: Cho, S.,Swaminathan, C.P.,Yang, J.,Kerzic, M.C.,Guan, R.,Kieke, M.C.,Kranz, D.M.,Mariuzza, R.A.,Sundberg, E.J.; Structural basis of affinity maturation and intramolecular cooperativity in a protein-protein interaction.; Structure, 13:1775-1787, 2005; PubMed: 16338399; DOI: 10.1016/j.str.2005.08.015

Experimental method

X-RAY DIFFRACTION (2 Å)