2APF

Crystal Structure of the A52V/S54N/K66E variant of the murine T cell receptor V beta 8.2 domain

Summary for 2APF

Entry DOI	10.2210/pdb2apf/pdb
Related	2APB 2APT 2APV 2APW 2APX 2AQ1 2AQ2 2AQ3
Descriptor	T cell receptor beta chain V, MALONIC ACID (3 entities in total)
Functional Keywords	t cell receptor, immune system
Biological source	Rattus norvegicus (Norway rat)
Total number of polymer chains	1
Total formula weight	12320.56
Authors	Cho, S.,Swaminathan, C.P.,Yang, J.,Kerzic, M.C.,Guan, R.,Kieke, M.C.,Kranz, D.M.,Mariuzza, R.A.,Sundberg, E.J. (deposition date: 2005-08-16, release date: 2006-03-21, Last modification date: 2018-04-04)
Primary citation	Cho, S.,Swaminathan, C.P.,Yang, J.,Kerzic, M.C.,Guan, R.,Kieke, M.C.,Kranz, D.M.,Mariuzza, R.A.,Sundberg, E.J. Structural basis of affinity maturation and intramolecular cooperativity in a protein-protein interaction. Structure, 13:1775-1787, 2005 Cited by PubMed: 16338399 DOI: 10.1016/j.str.2005.08.015 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation