2ANY
Expression, Crystallization and the Three-dimensional Structure of the Catalytic Domain of Human Plasma Kallikrein: Implications for Structure-Based Design of Protease Inhibitors
Summary for 2ANY
Entry DOI | 10.2210/pdb2any/pdb |
Related | 2ANW |
Descriptor | plasma kallikrein, light chain, PHOSPHATE ION, BENZAMIDINE, ... (4 entities in total) |
Functional Keywords | mutagenically deglycosyalted human plasma kallikrein protease domain; trypsin-like serine protease, blood clotting, hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Secreted: P03952 |
Total number of polymer chains | 1 |
Total formula weight | 27549.91 |
Authors | Tang, J.,Yu, C.L.,Williams, S.R.,Springman, E.,Jeffery, D.,Sprengeler, P.A.,Estevez, A.,Sampang, J.,Shrader, W.,Spencer, J.R.,Young, W.B.,McGrath, M.E.,Katz, B.A. (deposition date: 2005-08-11, release date: 2005-10-11, Last modification date: 2023-08-23) |
Primary citation | Tang, J.,Yu, C.L.,Williams, S.R.,Springman, E.,Jeffery, D.,Sprengeler, P.A.,Estevez, A.,Sampang, J.,Shrader, W.,Spencer, J.,Young, W.,McGrath, M.,Katz, B.A. Expression, crystallization, and three-dimensional structure of the catalytic domain of human plasma kallikrein. J.Biol.Chem., 280:41077-41089, 2005 Cited by PubMed: 16199530DOI: 10.1074/jbc.M506766200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
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