2AMV

THE STRUCTURE OF GLYCOGEN PHOSPHORYLASE B WITH AN ALKYL-DIHYDROPYRIDINE-DICARBOXYLIC ACID

Replaces:  1AMV

Summary for 2AMV

• Entry DOI: 10.2210/pdb2amv/pdb
• Descriptor: PROTEIN (GLYCOGEN PHOSPHORYLASE), PYRIDOXAL-5'-PHOSPHATE, 2,3-DICARBOXY-4-(2-CHLORO-PHENYL)-1-ETHYL-5-ISOPROPOXYCARBONYL-6-METHYL-PYRIDINIUM, ... (5 entities in total)
• Functional Keywords: glycogen phosphorylase, glycogen metabolism, diabetes, inhibitors, glycosyltransferase, transferase
• Biological source: Oryctolagus cuniculus (rabbit)
• Total number of polymer chains: 1
• Total formula weight: 98037.28

Authors

Zographos, S.E.,Oikonomakos, N.G.,Johnson, L.N. (deposition date: 1998-10-13, release date: 1998-10-21, Last modification date: 2011-07-13)

• Primary citation: Zographos, S.E.,Oikonomakos, N.G.,Tsitsanou, K.E.,Leonidas, D.D.,Chrysina, E.D.,Skamnaki, V.T.,Bischoff, H.,Goldmann, S.,Watson, K.A.,Johnson, L.N.; The structure of glycogen phosphorylase b with an alkyldihydropyridine-dicarboxylic acid compound, a novel and potent inhibitor.; Structure, 5:1413-1425, 1997; PubMed: 9384557; DOI: 10.1016/S0969-2126(97)00292-X

Experimental method

X-RAY DIFFRACTION (2.3 Å)