2AHX

Crystal structure of ErbB4/HER4 extracellular domain

Summary for 2AHX

• Entry DOI: 10.2210/pdb2ahx/pdb
• Descriptor: Receptor tyrosine-protein kinase erbB-4, 2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, ... (5 entities in total)
• Functional Keywords: x-ray crystallography; neuregulins; heparin-binding, cell cycle, signaling protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 141978.14

Authors

Bouyain, S.,Longo, P.A.,Li, S.,Ferguson, K.M.,Leahy, D.J. (deposition date: 2005-07-28, release date: 2005-09-27, Last modification date: 2020-07-29)

• Primary citation: Bouyain, S.,Longo, P.A.,Li, S.,Ferguson, K.M.,Leahy, D.J.; The extracellular region of ErbB4 adopts a tethered conformation in the absence of ligand; Proc.Natl.Acad.Sci.USA, 102:15024-15029, 2005; PubMed: 16203964; DOI: 10.1073/pnas.0507591102

Experimental method

X-RAY DIFFRACTION (2.396 Å)