2AEB
Crystal structure of human arginase I at 1.29 A resolution and exploration of inhibition in immune response.
Summary for 2AEB
| Entry DOI | 10.2210/pdb2aeb/pdb |
| Related | 1D3V 1WVA 2ZAV |
| Descriptor | Arginase 1, MANGANESE (II) ION, 2(S)-AMINO-6-BORONOHEXANOIC ACID, ... (4 entities in total) |
| Functional Keywords | hydrolase, binuclear manganese cluster, boronic acid inhibitor, perfectly twinned crystal, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm : P05089 |
| Total number of polymer chains | 2 |
| Total formula weight | 70163.51 |
| Authors | Di Costanzo, L.,Sabio, G.,Mora, A.,Rodriguez, P.C.,Ochoa, A.C.,Centeno, F.,Christianson, D.W. (deposition date: 2005-07-21, release date: 2005-09-06, Last modification date: 2023-08-23) |
| Primary citation | Di Costanzo, L.,Sabio, G.,Mora, A.,Rodriguez, P.C.,Ochoa, A.C.,Centeno, F.,Christianson, D.W. Crystal structure of human arginase I at 1.29 A resolution and exploration of inhibition in the immune response. Proc.Natl.Acad.Sci.Usa, 102:13058-13063, 2005 Cited by PubMed: 16141327DOI: 10.1073/pnas.0504027102 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.29 Å) |
Structure validation
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