2ADA

ATOMIC STRUCTURE OF ADENOSINE DEAMINASE COMPLEXED WITH A TRANSITION-STATE ANALOG: UNDERSTANDING CATALYSIS AND IMMUNODEFICIENCY MUTATIONS

「1ADA」から置き換えられました

2ADA の概要

• エントリーDOI: 10.2210/pdb2ada/pdb
• 分子名称: ADENOSINE DEAMINASE, ZINC ION, 6-HYDROXY-7,8-DIHYDRO PURINE NUCLEOSIDE, ... (4 entities in total)
• 機能のキーワード: hydrolase, amino, zinc cofactor, beta/alpha barrel, transition-state inhibitor
• 由来する生物種: Mus musculus (house mouse)
• 細胞内の位置: Cell membrane; Peripheral membrane protein; Extracellular side (By similarity): P03958
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 40381.24

構造登録者

Wilson, D.K.,Quiocho, F.A. (登録日: 1994-12-02, 公開日: 1995-03-31, 最終更新日: 2024-02-14)

• 主引用文献: Wilson, D.K.,Rudolph, F.B.,Quiocho, F.A.; Atomic structure of adenosine deaminase complexed with a transition-state analog: understanding catalysis and immunodeficiency mutations.; Science, 252:1278-1284, 1991; PubMed: 1925539

実験手法

X-RAY DIFFRACTION (2.4 Å)