2ACM
Solution structure of the SEA domain of human mucin 1 (MUC1)
Summary for 2ACM
Entry DOI | 10.2210/pdb2acm/pdb |
Descriptor | Mucin-1 (2 entities in total) |
Functional Keywords | auto-catalytic proteolysis, structural protein |
Biological source | Homo sapiens (human) More |
Cellular location | Apical cell membrane; Single-pass type I membrane protein. Isoform 5: Secreted. Isoform 7: Secreted. Isoform 9: Secreted. Mucin-1 subunit beta: Cell membrane: Q16615 Q16615 |
Total number of polymer chains | 2 |
Total formula weight | 13879.25 |
Authors | Macao, B.,Johansson, D.G.A.,Hansson, G.C.,Hard, T. (deposition date: 2005-07-19, release date: 2006-01-17, Last modification date: 2024-05-29) |
Primary citation | Macao, B.,Johansson, D.G.A.,Hansson, G.C.,Hard, T. Autoproteolysis coupled to protein folding in the SEA domain of the membrane-bound MUC1 mucin Nat.Struct.Mol.Biol., 13:71-76, 2006 Cited by PubMed: 16369486DOI: 10.1038/nsmb1035 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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