2A8U

Crystal Structure of Human Galactosyltransferase (GTB) Complexed with Beta-Methyl Lactoside

2A8U の概要

• エントリーDOI: 10.2210/pdb2a8u/pdb
• 関連するPDBエントリー: 1Z1Z 1ZIP 1ZJ0 1ZJ1 1ZJ2 1ZJ3
• 関連するBIRD辞書のPRD_ID: PRD_900076
• 分子名称: ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase), beta-D-galactopyranose-(1-4)-methyl beta-D-glucopyranoside, URIDINE-5'-DIPHOSPHATE, ... (7 entities in total)
• 機能のキーワード: gtb, blood group, abo(h), glycosyltransferase, retaining, transferase
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein: P16442
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 36010.27

構造登録者

Letts, J.A.,Rose, N.L.,Fang, Y.R.,Barry, C.H.,Borisova, S.N.,Seto, N.O.,Palcic, M.M.,Evans, S.V. (登録日: 2005-07-09, 公開日: 2005-12-13, 最終更新日: 2023-11-29)

• 主引用文献: Letts, J.A.,Rose, N.L.,Fang, Y.R.,Barry, C.H.,Borisova, S.N.,Seto, N.O.,Palcic, M.M.,Evans, S.V.; Differential Recognition of the Type I and II H Antigen Acceptors by the Human ABO(H) Blood Group A and B Glycosyltransferases.; J.Biol.Chem., 281:3625-3632, 2006; PubMed: 16326711; DOI: 10.1074/jbc.M507620200

実験手法

X-RAY DIFFRACTION (1.69 Å)