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2A5R

Complex of tetra-(4-n-methylpyridyl) porphin with monomeric parallel-stranded DNA tetraplex, snap-back 3+1 3' G-tetrad, single-residue chain reversal loops, GAG triad in the context of GAAG diagonal loop, C-MYC promoter, NMR, 6 struct.

Summary for 2A5R
Entry DOI10.2210/pdb2a5r/pdb
Related1D6D 1EEG 1JJP 1Y8D 2A5P
Descriptor5'-D(*TP*GP*AP*GP*GP*GP*TP*GP*GP*IP*GP*AP*GP*GP*GP*TP*GP*GP*GP*GP*AP*AP*GP*G)-3', (1Z,4Z,9Z,15Z)-5,10,15,20-tetrakis(1-methylpyridin-1-ium-4-yl)-21,23-dihydroporphyrin (2 entities in total)
Functional Keywordsmonomeric parallel-stranded quadruplex; c-myc promoter 3+1 g-tetrad; single nucleotide chain reversal loop; gag triad; gaag loop, dna
Biological sourceHomo sapiens (human)
Total number of polymer chains1
Total formula weight8380.76
Authors
Phan, A.T.,Kuryavyi, V.V.,Gaw, H.Y.,Patel, D.J. (deposition date: 2005-06-30, release date: 2005-07-26, Last modification date: 2011-07-13)
Primary citationPhan, A.T.,Kuryavyi, V.,Gaw, H.Y.,Patel, D.J.
Small-molecule interaction with a five-guanine-tract G-quadruplex structure from the human MYC promoter.
Nat.Chem.Biol., 1:167-173, 2005
Cited by
PubMed: 16408022
DOI: 10.1038/nchembio723
PDB entries with the same primary citation
Experimental method
SOLUTION NMR
Structure validation

217705

数据于2024-03-27公开中

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